Publications

Azetukalner, a Novel KV7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial

Abstract

Methods
Physician data from the Centers for Medicare & Medicaid Services National Downloadable File was combined with socioeconomic data from the Area Deprivation Index (ADI) Neighborhood Atlas (eMethods and eTable in Supplement 1). ADI is a validated measure of neighborhood socioeconomic disadvantage, incorporating factors such as income, education, employment, and housing quality. We performed a cross-sectional study by analyzing 2 cohorts of newly licensed physicians (2015 and 2020) for which ADI ranks are available. This study analyzed publicly available, open-government data and was therefore not considered human participants research. Institutional review board approval and informed consent were not required in accordance with federal guidelines (45 CFR § 46). STROBE reporting guidelines were followed.

Date
May 28, 2025
Authors
Navapat Nananukul, Mayank Kejriwal
Journal
JAMA Network Open
Volume
8
Issue
5
Pages
e2512474